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9 15 f Hot flashes 24 Sweating 19 Joint pain 16 Nottingham Breast Unit 81 2 Observational 16 100 NS Anastrozole goserelin Tamoxifen goserelin for MBC ORR e, g 75 NS ChiCTR ONC 13003946 57 1 2 Phase II 44 100 89 Exemestane goserelin Adjuvant ET CT and ET CT for MBC Median PFS months 13 20 h Hot flashes 55 Arthralgia 52 Fatigue 39 Myalgia 21 Nottingham Breast Unit 53 2 Observational 13 100 NS Exemestane goserelin Anastrozole goserelin for ABC required, prior tamoxifen allowed CBR g 38 NS Kyushu University 58 2 Retrospective 14 100 100 AI GnRHa Tamoxifen GnRHa, CT for EBC or MBC CBR 71 propecia medication