I worked for Huge Cable Corp. a few years ago and got training in the design of their high end cabling. It *IS* better but it's all relative to the capabilities of your ears. We had a sales room that had identicle audio setups, side by side with the only difference, the cableing. Monster cable on one, radio hut kicked ass on the other. And there was a substantial difference in dynamic range, overall gain and top end and low end frequency response. I checked the set up myself and dang if it wasn't real.
That being said, I still have regular cables in my home system.